What negative impact did gold & silver mining have in the west

The gold and silver mining negatively impacts the west by having harsh conditions. The people mined for several hours a day and barely had any sleep. Meaning many people died and starved during the process.

Ifound the exercise on the internet. attached is the list mentioned above.in order for a compound to be considered optically active it can't have any axis or plan of symmetry. the molecule  shouldn't also  be superimposable on its mirror image.with such considerations, the compounds that are optically active are: -third compound on the first image is optically active; -second and third compound from the second image are optically actives.