Why did the settlement and colonization of South Africa by the white Europeans cause conflict with the native Black Africans?

The first Europeans to enter Southern Africa were the Portuguese, who from the 15th century edged their way around the African coast in the hope of outflanking Islam, finding a sea route to the riches of India, and discovering additional sources of food. They reached the Kongo kingdom in northwestern Angola in 1482–83; early in 1488 Bartolomeu Dias rounded the southern tip of the continent; and just over a decade later Vasco da Gama sailed along the east coast of Africa before striking out to India. Although the voyages were initially unpromising, they marked the beginning of the integration of the subcontinent into the new world economy and the dominance of Europeans over the indigenous inhabitants.

i only have part a but here is the first one: - lewis and clark are born

- lewis marries sacajawea and clark is jealous  

- clark drowns lewis and then goes to jail