What action would most likely require a referendum to accomplish?

in 342 bc j._c. egypt fell into the hands of the persians, under the reign of nectanebo ii

greek city-states unite in a revolt against the persian empire at the beginning of the fifth century bc. j.-c  

from the year 660 or 659 bc ad, cyrus preached the revolt against the medes to deliver the persians.

it is a part of john locke's natural rights popular during the age of enlightenment that people had inalienable rights to life, liberty and property. this was reflected by thomas jefferson in his declaration of independence as rights to life,liberty and the pursuit of happiness.

another line in the declaration of independence is that people have certain rights just because they are human. humans are capable of obeying the three natural rights john locke mentioned making them governable by these laws and therefore entitled to these rights as well.