What effects are felt when people do not believe in the bible's inspiration?

The Bible like many other religious scriptures broadly outlines a set of principles to live by and an answer to what meaning life and living has. So one effect of not following the bibles inspiration would be living life with fewer constraints as there are fewer rules, teachings, and commandments to follow. This might give the non-follower a greater sense of freedom to the follower. However, another effect the non-follower might feel is a sense of existential nihilism as life without an afterlife or mission might make the non-follower feel theirs is pointless. This might make the non-follower more prone to psychiatric disorders and general neuroticism.