Why is subgroup analysis problematic in research? limit your response to one sentence.

SUMMARY: The randomized ISAT demonstrated the superiority of endovascular treatment in patients with ruptured intracranial aneurysms considered suitable for either clipping or coiling. A later publication proposed a second look at the results, demonstrating that older patients with ruptured MCA aneurysms appeared to benefit from clipping, in disagreement with the general findings of the trial. Subgroup analyses in randomized trials and observational studies examine whether effects of interventions differ between subgroups according to the characteristics of patients. However, many apparent subgroup effects have been shown to be spurious. Misleading subgroup effects can result in withholding efficacious treatment from patients who would benefit or can encourage ineffective or potentially harmful treatments for patients who would fare better without. Some guidelines for the prudent interpretation of subgroup findings are reviewed.

United states v.  nixon, 418  u.s.  683 (1974),  was  a landmark  united states supreme court case  that resulted in a unanimous  decision  against president richard  nixon, ordering him to deliver tape recordings  and  other subpoenaed materials to a  federal  district  court.

d - failures.

the only attempted british colony in north america before 1600 was roanoke, virginia, which was a total failure. england claimed several areas, including newfoundland, but made no sustainable attempts to colonize them before 1600.

mark brainliest