You have engineered a protein that contains a nuclear localization signal, a nuclear export signal, a C-terminal peroxisomal targeting signal, and an import signal for the endoplasmic reticulum. with all of these signal sequences, where would you expect to find the protein after its synthesis?

The correct answer is - Endoplasmic reticulum

Explanation:

In this case, the N-terminal endoplasmic reticulum signal sequence of the engineered protein is recognized primarily. This signal is used to target the particular protein co-translationally, to the endoplasmic reticulum for post-translational modifications or changes.

Such post-modifications are glycosylation that taken place in the lumen of the endoplasmic reticulum. Other than Glycosylation Protein phosphorylation , Sumoylation and Ubiquitination, are other changes or modifications.

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