The sequencing of the human genome lead to the realization that chromosome 19 contains many genes while chromosomes 13 and Y contain relatively few. This finding implies what about the density of genes in a genome

You are studying a protein that you call protein x. there is an aspartic acid at a key position in protein x which is important in the folding and stabilization of that protein. if this aspartic acid is changed to a different amino acid, which type of amino acid substitutions is most likely to allow the protein to fold normally?