Morphogens determine the formation of the and control the expression of transcription factors of phase two.

Morphogens influence morphogenesis which is the defined as the development of organisms from an embryo. Tissues are made from differentiated cells while differentiated cells are developed from embryonic stem cells.
Morphogens are molecules, such as cell signals, radionuclides, and toxins, etcetera that influence the silencing and transcription of genes hence determining them.

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