In research on aging (both cellular aging and organismal aging), it has been found that aged cells do not progress through the cell cycle as they had previously. which of the following would provide evidence that this is related to cell signaling? in research on aging (both cellular aging and organismal aging), it has been found that aged cells do not progress through the cell cycle as they had previously. which of the following would provide evidence that this is related to cell signaling? atp production decreases. camp levels change very frequently. enzymatic activity declines. growth factor ligands do not bind as efficiently to receptors. their lower hormone concentrations elicit a lesser response.