Which of the following statements correctly compares water-soluble and lipid-soluble hormones?
select one:
a. only lipid-soluble hormones require a receptor.
b. both types of hormone almost always stimulate increases in mrna transcription.
c. lipid-soluble hormones usually activate g-protein coupled receptors
d. both types of hormone are carried in the blood attached to a carrier protein.
e. only water-soluble hormones use second messengers.

The correct answer is option E. only water-soluble hormones use second messengers.

Explanation:

Water soluble hormones can not diffuse through cell membranes as only lipid soluble molecules can pass through the cell membranes and these hormons are not lipid soluble molecules,

These water hormones are usually glycoproteins, peptide and catecholamnies such as TSH, FSH, LH and insulin. these hormones need second messengers because there receptors are present on the plasma membrane.

Thus, the correct answer is option - e.  only water-soluble hormones use second messengers.

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